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Cannabidiol is an active chemical compound of the cannabis plant.  It is one of the cannabinoids found in the cannabis plant.  There are more than 80 cannabinoids, which consists of a group of closely related compounds found in the cannabis plant.  Each cannabinoid have its own benefits and potential side effects on the human body. Cannabidiol is one of these cannabinoids and accounts for up to 40% of the plant’s extract., and after it has been extracted it is typically taken as CBD oil tincture rather than smoked.  CBD is the reason for many people changing their views about use of marijuana.  However, it is important to understand that marijuana also contain Tetrahydrocannabinol (THC) which has adverse effects on the mind.  This is what made cannabis plant to be one of the most persecuted plants on the planet.


These two chemicals are both contained in marijuana, but they serve different purposes, and also have different side effects.  While the THC in marijuana is going to get you high, CBD poses huge benefits from a medicinal point of view – and it does not have the same side effects on the body as THC.


A clinical research on cannabidiol included preliminary studies of anxiety, cognition, movement disorders, and pain. It was found that the CBD, after it has been extracted from cannabis plant and taken as CBD oil, can relieve anxiety, reduce the cognitive symptoms of stress, anxiety and depression, ease symptoms of ailments like chronic pain and movement disorders.

Human bodies contain the endocannabinoid system (ECS), which is involved in regulating a variety of functions including sleep, appetite, pain and immune system response.  Studies have shown that CBD may help reduce chronic pain by impacting endocannabinoid receptor activity, reducing inflammation and interacting with neurotransmitters.  Several human studies have found that a combination of CBD and THC is effective in treating pain related to multiple sclerosis and arthritis.  An oral spray called Sativex, which is a combination of THC and CBD, is approved in several countries to treat pain related to multiple sclerosis.


CBD has few side effects and is considered a safe substance to take. The known side effects of CBD include:

  • Inhibition of hepatic drug metabolism/decreased activities of p-glycoprotein and other drug transporters, caused by the high dose of cannabidiol.
  • Dry mouth, caused by the involvement of the endocannabinoid system in the inhibition of saliva secretion.
  • Increased tremor in certain groups, also caused by the high dose, and reducing the serving should reduce this potential side effect.
  • Low blood pressure. If you are taking medication for blood pressure, you should consult your doctor before taking CBD.
  • Lightheadedness, which is  temporary and can often be resolved by drinking a cup of coffee or tea.
  • Drowsiness, only in higher dose.  Avoid driving or operating machinery if you are affected this way.


THC is the principal psychoactive constituent of cannabis.  It stimulates cells in the brain to release dopamine, creating euphoria. Dopamine is a type of neurotransmitter. Your body makes it, and your nervous system uses it to send messages between nerve cells.  THC also interferes with how information is processed in the hippocampus, which is part of the brain responsible for forming new memories. THC can induce hallucinations, change thinking and cause delusions.  The effects of smoking marijuana are felt as soon as the THC enters the bloodstream.

Since the body and mind are connected, the psychoactive effects of THC in cannabis are both psychological and physiological.  Because the THC reduces the short term memory, it can be incredibly beneficial for those suffering from traumatic memories, like people with PTSD.  Hence the promising findings that tetrahydrocannabinol can treat a range of psychological disorders related to trauma.  It can improve mood disorders like depression and anxiety. Some have even suggested THC can help people with ADHD.  However,  long-term effects of cannabis use can hasten the onset of certain psychological disorders. If you’re more prone to schizophrenia or psychosis, regular cannabis use can make you more vulnerable to those symptoms.

THC acts as a powerful anti-inflammatory.  Inflammation is an underlying factor that contributes to or complicates a wide range of diseases, which means tetrahydrocannabinol has a role to play in treating all of them, including the depression.  While THC can act as a powerful anti-inflammatory, it can also reduce the immune system’s effectiveness.

THC can ease the harsh side-effects of cancer treatments like chemotherapy and radiation.  It can cause cancer cells to eat themselves, resulting in shrunken tumors and a reduction in the prevalence of cancer cells.

It can also stimulate the release of the “hunger hormone” ghrelin and help ease nausea.  The FDA has approved a synthetic form of THC as an appetite stimulant and an antiemetic for AIDS and chemotherapy patients.  Cannabis topical creams are quickly becoming popular as pain relievers and skincare products. The ability to absorb THC into the skin means people can use the cannabinoid for therapeutic benefits without the psychotropic effects.


The most potent THC-dominant strains include;

  • Godfather OG // Indica // 34.04 percent THC
  • Super Glue // Hybrid // 32.14 percent THC
  • Strawberry Banana // Hybrid // 31.62 percent THC
  • Venom OG Kush // Indica // 31.04 percent THC


  1. Hi Sandicasi,

    Excellent article, I really liked the reading! One of my friends used to smoke marijuana, and I remember that she was getting paranoic when smoking. That’s the reason why she stops:) I didn’t know there was a difference between THC and CBD. I just would like to know something. I hope you can help me with that. One of my friends suffers from Bipolarity, and I was wondering if CBD could help him when he is in the depression phase?

    Also, what would you suggest for people that panic when being in the crowds?

    Thank you for this excellent post!

    1. Hi Daniella,

      Thank you for stopping by.  I appreciate your time and comments.  Thank you for asking this question because I should have mentioned that people suffering from major depression,, like Bipolar must consult a medical practitioner so that they can be diagnosed to determine the proper treatment, because depression can be triggers by many factors, and some may be medical.  Thyroid for example can cause depression.  Inflammation can also cause depression, and CBD has the power to reduce inflammation, and is also anti-psychotic.  CBD reduce the cognitive symptoms of depression, like fatigue,

  2. Hello Sandikazi!

    You wrote a very useful article that helps us better understand the substances from cannabis and what they do to us. Well, at least with CBD we may feel safe because it is not illegal / persecuted by law, regardless of its side effects that can be handled if people use CBD carefully. As for THC, it is a true mix of pros and cons, and it turns out that we should be even more careful at using it, besides the legal aspects.

    And I think that Cannabidiol (aka the good part of cannabis) may be used also by people with insomnia, for helping them sleep better if they apply a tincture one or two hours before going to bed.

    Best regards,


    1. Thank you Peter for stopping by.  I highly appreciate your time and comments.

      All the best.


  3. Great post you have here and I must say you have shared a lot if information here concerning CBD oil and what makes it exceptional. Thanks for sharing here. For a truth, we must say that cbd has become so much expanded and well  established. Great one here because it actually works well beyond whatever we could expect from it. Thanks

    1. Thank you for reading.  I highly appreciate it,

      All the best,


  4. Hi, I think this article about cannabidoil is very interesting. I would not say that I am depressed.. yet but I have recently been battling a cancer diagnosis and I had surgery just a few days ago to remove the tumour. I have been recommended similar products as it is said they can help with the dizziness one might get from, the whole situation of a cancer diagnosis I guess. Do you know if there is any research on this? As the dizziness ir truly becoming a big problem for me. 

    Thank you for this very informative article about the and cannabidoil.

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